Pathology of Genetically Engineered and Other Mutant Mice – John P. Sundberg, Jerrold M. Ward, Peter Vogel

Detailní popis produktu

The book is written by experienced veterinary and medical pathologists working in veterinary medical colleges, medical colleges, and research institutes. Covering the latest discoveries in mouse pathology resulting from advancements in biotechnology research over the last 30 years, this singular and accessible resource is a must-read for veterinary and medical pathologists and researchers working with genetically engineered and other mice. 

Readers will also benefit from: 

• A thorough introduction to mouse pathology and mouse genetic nomenclature, as well as databases useful for analysis of mutant mice
• An exploration of concepts related to validating animal models, including the Cinderella Effect
• Practical discussions of basic necropsy methods and grading lesions for computational analyses
• Concise diagnostic approaches to the respiratory tract, the oral cavity and GI tract, the cardiovascular system, the liver and pancreas, the skeletal system, and other tissues 

As a one-stop and up to date reference on mouse pathology, Pathology of Genetically Engineered and Other Mutant Mice is an essential book for veterinary and medical pathologists, as well as for scientists, researchers, and toxicologists whose work brings them into contact with genetically modified mice.

ABOUT THE AUTHOR

The editors 

John P. Sundberg, DVM, PhD, DACVP, is Professor at The Jackson Laboratory in Bar Harbor, Maine, USA and an Adjunct Professor in the Department of Dermatology, Vanderbilt University Medical Center in Nashville, TN, USA. 

Jerrold M. Ward, DVM, PhD, DACVP, FIATP,is an Adjunct Faculty member at The Jackson Laboratory, Bar Harbor, Maine, USA and Adjunct Professor in the Department of Biomedical Sciences at Cornell University College of Veterinary Medicine in Ithaca, New York, USA. 

Peter Vogel, DVM, PhD,DACVP, is Director of the Veterinary Pathology Core Laboratory at St. Jude Children’s Research Hospital in Memphis, Tennessee, USA.